ALDH5A1 antibody (C-Term)

Catalog No. ABIN6990982

This Rabbit Polyclonal antibody specifically detects ALDH5A1 in ELISA and WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ALDH5A1 antibody (C-Term) (ABIN6990982)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ALDH5A1 Antibody

Binding Specificity: C-Term

Purification: Aldh5A1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Aldh5A1 antibody was raised against a 22 amino acid synthetic peptide near the carboxy terminus of the human Aldh5A1. The immunogen is located within the last 50 amino acids of Aldh5A1.

Isotype: IgG

Application Details

Application Notes: Aldh5A1 antibody can be used for detection of Aldh5A1 by Western blot at 0.25 - 0.5 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Aldh5A1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Aldh5A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: Aldh5A1

Background: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.

Molecular Weight: Predicted: 60 kDa

Observed: 60 kDa

Gene ID: 7915

NCBI Accession: NP_733936

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process