LRFN3 antibody (AA 380-430)

Catalog No. ABIN6991077

Product Details anti-LRFN3 Antibody

Target: LRFN3 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 3 (LRFN3))

Binding Specificity: AA 380-430

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRFN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody is predicted to not cross-react with other members of the LRFN family.

Purification: LRFN3 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRFN3 antibody was raised against a 16 amino acid synthetic peptide near the center of human LRFN3. The immunogen is located within amino acids 380 - 430 of LRFN3.

Isotype: IgG

Application Details

Application Notes: LRFN3 antibody can be used for detection of LRFN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRFN3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRFN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LRFN3

Target: LRFN3 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 3 (LRFN3))

Alternative Name: LRFN3 (LRFN3 Products)

Synonyms: FIGLER1 antibody, SALM4 antibody, A530045B06Rik antibody, Salm4 antibody, LRFN3 antibody, leucine rich repeat and fibronectin type III domain containing 3 antibody, LRFN3 antibody, Lrfn3 antibody

Background: LRFN3 Antibody: LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Gene ID: 79414

NCBI Accession: NP_078785

UniProt: Q9BTN0

Pathways: Synaptic Membrane