GID8/C20orf11 antibody (C-Term)

Catalog No. ABIN6991171

Product Details anti-GID8/C20orf11 Antibody

Target: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GID8/C20orf11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: TWA1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TWA1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TWA1. The immunogen is located within the last 50 amino acids of TWA1.

Isotype: IgG

Application Details

Application Notes: TWA1 antibody can be used for detection of TWA1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TWA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TWA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GID8/C20orf11

Target: GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))

Alternative Name: TWA1 (GID8 Products)

Synonyms: C20orf11 antibody, TWA1 antibody, Bwk1 antibody, 2310003C23Rik antibody, C13H20orf11 antibody, GID complex subunit 8 homolog antibody, GID complex subunit 8 antibody, GID8 antibody, Gid8 antibody

Background: TWA1 Antibody: TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.

Gene ID: 54994

NCBI Accession: NP_060366

UniProt: Q9NWU2