PGCC1 Antibody is affinity chromatography purified via peptide column.
Immunogen
PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1. The immunogen is located within the last 50 amino acids of PGCC1.
FAM120B
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
FITC
Application Notes
PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PGCC1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
PGCC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
FAM120B
(Family with Sequence Similarity 120B (FAM120B))
4932442K08Rik antibody, AW049283 antibody, AW413338 antibody, CCPG antibody, Pgcc1 antibody, mKIAA1838 antibody, KIAA1838 antibody, PGCC1 antibody, dJ894D12.1 antibody, RGD1310304 antibody, family with sequence similarity 120B antibody, family with sequence similarity 120, member B antibody, FAM120B antibody, Fam120b antibody
Background
PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.