ProSAPiP1 antibody (C-Term)

Catalog No. ABIN6991188

Product Details anti-ProSAPiP1 Antibody

Target: ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))

Binding Specificity: AA 590-640, C-Term

Reactivity: Mouse, Rat, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ProSAPiP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: Prosapip1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1.

Isotype: IgG

Application Details

Application Notes: Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Prosapip1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Prosapip1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ProSAPiP1

Target: ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))

Alternative Name: Prosapip1 (PROSAPIP1 Products)

Synonyms: PROSAPIP1 antibody, RP5-1187M17.10 antibody, Prosapip1 antibody, leucine zipper tumor suppressor family member 3 antibody, leucine zipper, putative tumor suppressor family member 3 antibody, LZTS3 antibody, Lzts3 antibody

Background: Prosapip1 Antibody: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Gene ID: 9762

NCBI Accession: NP_055546

UniProt: O60299