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RUSC2 antibody (C-Term)

RUSC2 Reactivity: Human ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991196
  • Target See all RUSC2 Antibodies
    RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))
    Binding Specificity
    • 9
    • 8
    • 6
    • 1
    • 1
    AA 1410-1460, C-Term
    Reactivity
    • 17
    • 2
    Human
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This RUSC2 antibody is un-conjugated
    Application
    • 16
    • 12
    • 12
    • 6
    • 3
    • 2
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    At least three isoforms are known to exist, this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.
    Purification
    RUSC2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2. The immunogen is located within amino acids 1410 - 1460 of RUSC2.
    Isotype
    IgG
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    Discover our top product RUSC2 Primary Antibody
  • Application Notes
    RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))
    Alternative Name
    RUSC2 (RUSC2 Products)
    Synonyms
    MGC142511 antibody, DKFZp469H2039 antibody, Iporin antibody, AI840675 antibody, mKIAA0375 antibody, RUN and SH3 domain containing 2 antibody, RUSC2 antibody, rusc2 antibody, Rusc2 antibody
    Background
    RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
    Gene ID
    9853
    NCBI Accession
    NP_001098673
    UniProt
    Q8N2Y8
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