PLEKHM2 antibody (C-Term)

Catalog No. ABIN6991225

Product Details anti-PLEKHM2 Antibody

Target: PLEKHM2 (Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHM2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: PLEKHM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: PLEKHM2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM2. The immunogen is located within the last 50 amino acids of PLEKHM2.

Isotype: IgG

Application Details

Application Notes: PLEKHM2 antibody can be used for detection of PLEKHM2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PLEKHM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PLEKHM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PLEKHM2

Target: PLEKHM2 (Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))

Alternative Name: PLEKHM2 (PLEKHM2 Products)

Synonyms: zgc:194971 antibody, RP11-169K16.1 antibody, SKIP antibody, 2310034J19Rik antibody, AI854247 antibody, mKIAA0842 antibody, pleckstrin homology and RUN domain containing M2 antibody, pleckstrin homology domain containing, family M (with RUN domain) member 2 antibody, PLEKHM2 antibody, plekhm2 antibody, Plekhm2 antibody

Background: PLEKHM2 Antibody: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Gene ID: 23207

UniProt: Q8IWE5