Synaptogyrin 1 antibody (AA 120-170)

Catalog No. ABIN6991254

Product Details anti-Synaptogyrin 1 Antibody

Target: Synaptogyrin 1 (SYNGR1)

Binding Specificity: AA 120-170

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptogyrin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: SYNGR1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SYNGR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SYNGR1. The immunogen is located within amino acids 120 - 170 of SYNGR1.

Isotype: IgG

Application Details

Application Notes: SYNGR1 antibody can be used for detection of SYNGR1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYNGR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SYNGR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Synaptogyrin 1

Target: Synaptogyrin 1 (SYNGR1)

Alternative Name: SYNGR1 (SYNGR1 Products)

Synonyms: p7d11 antibody, syngr1 antibody, zgc:101712 antibody, P7D11 antibody, MGC180663 antibody, R75468 antibody, Syngr1b antibody, p29 antibody, synaptogyrin 1 L homeolog antibody, synaptogyrin 1 antibody, synaptogyrin 1a antibody, syngr1.L antibody, SYNGR1 antibody, syngr1a antibody, syngr1 antibody, Syngr1 antibody

Background: SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia, however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Gene ID: 9145

UniProt: O43759

Pathways: Regulation of long-term Neuronal Synaptic Plasticity