DCAF12 antibody (C-Term)

Catalog No. ABIN6991318

Product Details anti-DCAF12 Antibody

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Binding Specificity: AA 390-440, C-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This DCAF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: TCC52 Antibody is affinity chromatography purified via peptide column.

Immunogen: TCC52 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TCC52. The immunogen is located within amino acids 390 - 440 of TCC52.

Isotype: IgY

Application Details

Application Notes: TCC52 antibody can be used for detection of TCC52 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TCC52 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TCC52 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DCAF12

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Alternative Name: TCC52 (DCAF12 Products)

Synonyms: CT102 antibody, KIAA1892 antibody, TCC52 antibody, WDR40A antibody, 1500001L20Rik antibody, 5830424K06Rik antibody, AA420338 antibody, AI851081 antibody, Wdr40a antibody, wdr40a antibody, wu:fb93d04 antibody, zgc:154031 antibody, wdr40b antibody, dcaf12 antibody, wdr40a-a antibody, DDB1 and CUL4 associated factor 12 antibody, DDB1 and CUL4 associated factor 12 L homeolog antibody, DCAF12 antibody, Dcaf12 antibody, dcaf12 antibody, dcaf12.L antibody

Background: TCC52 Antibody: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.

Gene ID: 25853

NCBI Accession: NP_056212

UniProt: Q5T6F0