OGFOD2 antibody (AA 140-190)

Catalog No. ABIN6991487

Product Details anti-OGFOD2 Antibody

Target: OGFOD2 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))

Binding Specificity: AA 140-190

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGFOD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist, this antibody will only detect the two larger isoforms.

Purification: OGFOD2 Antibody is affinity chromatography purified via peptide column.

Immunogen: OGFOD2 antibody was raised against a 17 amino acid synthetic peptide near the center of human OGFOD2. The immunogen is located within amino acids 140 - 190 of OGFOD2.

Isotype: IgG

Application Details

Application Notes: OGFOD2 antibody can be used for detection of OGFOD2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: OGFOD2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: OGFOD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for OGFOD2

Target: OGFOD2 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))

Alternative Name: OGFOD2 (OGFOD2 Products)

Synonyms: RGD1310594 antibody, 1300006G11Rik antibody, 5730405M13Rik antibody, AU041636 antibody, AW552395 antibody, ogfod2 antibody, 2-oxoglutarate and iron-dependent oxygenase domain containing 2 antibody, 2-oxoglutarate and iron dependent oxygenase domain containing 2 antibody, Ogfod2 antibody, OGFOD2 antibody, ogfod2 antibody

Background: OGFOD2 Antibody: OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.

Gene ID: 79676

NCBI Accession: NP_078899

UniProt: Q6N063