TYW3 antibody (AA 160-210)

Catalog No. ABIN6991542

Product Details anti-TYW3 Antibody

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Binding Specificity: AA 160-210

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYW3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.

Purification: TYW3 Antibody is affinity chromatography purified via peptide column.

Immunogen: TYW3 antibody was raised against a 17 amino acid synthetic peptide near the center of human TYW3. The immunogen is located within amino acids 160 - 210 of TYW3.

Isotype: IgG

Application Details

Application Notes: TYW3 antibody can be used for detection of TYW3 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TYW3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: TYW3 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TYW3

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Alternative Name: TYW3 (TYW3 Products)

Synonyms: C1orf171 antibody, 5230400J09Rik antibody, tRNA-yW synthesizing protein 3 homolog L homeolog antibody, tRNA-yW synthesizing protein 3 homolog antibody, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antibody, tyw3.L antibody, TYW3 antibody, Tyw3 antibody

Background: TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.

Gene ID: 127253

UniProt: Q6IPR3