L1TD1 antibody (C-Term)

Catalog No. ABIN6991565

Product Details anti-L1TD1 Antibody

Target: L1TD1 (LINE-1 Type Transposase Domain Containing 1 (L1TD1))

Binding Specificity: AA 690-740, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L1TD1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: L1TD1 antibody is predicted to not cross-react with other ECAT protein family members

Purification: L1TD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: L1TD1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human L1TD1. The immunogen is located within amino acids 690 - 740 of L1TD1.

Isotype: IgG

Application Details

Application Notes: L1TD1 antibody can be used for detection of L1TD1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: L1TD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: L1TD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for L1TD1

Target: L1TD1 (LINE-1 Type Transposase Domain Containing 1 (L1TD1))

Alternative Name: L1TD1 (L1TD1 Products)

Synonyms: ECAT11 antibody, RP5-1155K23.3 antibody, AA546746 antibody, AB211064 antibody, D76865 antibody, LINE1 type transposase domain containing 1 antibody, LINE-1 type transposase domain containing 1 antibody, L1TD1 antibody, L1td1 antibody

Background: L1TD1 Antibody: L1TD1 (ECAT11) is a member of the family of Embryonic Stem Cell Associated Transcripts (ECAT) that play an important role in stem cell biology. ECAT4 (Nanog) is a master regulator for the maintenance of mESC and hESC. ECAT5 was identified to be Embryonic stem cell expressed Ras (ERas), a Ras-like oncogene that is important in regulating mESC proliferation. ECAT9 (GDF3) is an important factor that helps maintain mESC pluripotency by inhibiting bone morphogenetic protein (BMP) signaling. L1TD1 is highly enriched in undifferentiated hESC and L1TD1 is a target gene of Nanog.

Gene ID: 54596

NCBI Accession: NP_061952

UniProt: Q5T7N2