SPINK2 antibody (C-Term)

Catalog No. ABIN6991639

Product Details anti-SPINK2 Antibody

Target: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINK2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: SPINK2 antibody is predicted to not cross-react with other SPINK family members.

Purification: SPINK2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SPINK2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of mouse SPINK2. The immunogen is located within the last 50 amino acids of SPINK2.

Isotype: IgG

Application Details

Application Notes: SPINK2 antibody can be used for detection of SPINK2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SPINK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SPINK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SPINK2

Target: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Alternative Name: SPINK2 (SPINK2 Products)

Synonyms: 1700007F22Rik antibody, AV038945 antibody, HUSI-II antibody, serine peptidase inhibitor, Kazal type 2 antibody, serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) antibody, Spink2 antibody, SPINK2 antibody

Background: SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.

Molecular Weight: Predicted: 15 kDa

Observed: 18 kDa

Gene ID: 69982

NCBI Accession: NP_001276693

UniProt: Q8BMY7