PPHLN1 antibody (AA 160-210)

Catalog No. ABIN6991643

The Rabbit Polyclonal anti-PPHLN1 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect PPHLN1 in samples from Human and Mouse.

Quick Overview for PPHLN1 antibody (AA 160-210) (ABIN6991643)

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPHLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PPHLN1 Antibody

Binding Specificity: AA 160-210

Purification: Periphilin Antibody is affinity chromatography purified via peptide column.

Immunogen: Periphilin antibody was raised against a 16 amino acid synthetic peptide near the center of human Periphilin. The immunogen is located within amino acids 160 - 210 of Periphilin.

Isotype: IgG

Application Details

Application Notes: Periphilin antibody can be used for detection of Periphilin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Periphilin Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Periphilin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PPHLN1

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Alternative Name: Periphilin

Background: Periphilin Antibody: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.

Gene ID: 51535

NCBI Accession: NP_958848

UniProt: Q8NEY8