TSC22D3 Antibody is affinity chromatography purified via peptide column.
Immunogen
Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3. The immunogen is located within amino acids 40 - 90 of TSC22D3.
TSC22D3
Reactivity: Human
WB, IF
Host: Mouse
Monoclonal
1E11
unconjugated
Application Notes
TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
TSC22D3 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
TSC22D3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
TSC22D3 Antibody: The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κ,B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κ,B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.