IL15RA antibody (AA 40-90)

Catalog No. ABIN6991821

Product Details anti-IL15RA Antibody

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Binding Specificity: AA 40-90

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of IL-15RA are known to exist.

Purification: IL-15RA Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA. The immunogen is located within amino acids 40 - 90 of IL-15RA.

Isotype: IgG

Application Details

Application Notes: IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-15RA Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-15RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL-15RA (IL15RA Products)

Synonyms: IL15RA antibody, CD215 antibody, AA690181 antibody, IL-15RA antibody, interleukin 15 receptor subunit alpha antibody, interleukin 15 receptor, alpha chain antibody, IL15RA antibody, Il15ra antibody

Background: IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.

Molecular Weight: Predicted: 26, 30, 38 kDa

Observed: 30 kDa

Gene ID: 3601

NCBI Accession: NP_001243694

UniProt: Q13261

Pathways: JAK-STAT Signaling