SDPR antibody (N-Term)

Catalog No. ABIN6991833

Product Details anti-SDPR Antibody

Target: SDPR (Serum Deprivation Response (SDPR))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDPR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: It is predicted to not cross-react with other members of the cavin family.

Purification: SDPR Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR. The immunogen is located within the first 50 amino acids of SDPR.

Isotype: IgG

Application Details

Application Notes: SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SDPR Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SDPR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SDPR

Target: SDPR (Serum Deprivation Response (SDPR))

Alternative Name: SDPR (SDPR Products)

Synonyms: CAVIN2 antibody, PS-p68 antibody, SDR antibody, cavin-2 antibody, sdr antibody, MGC84112 antibody, sdprb antibody, wu:fb39c08 antibody, wu:fk90b02 antibody, zgc:92231 antibody, caveolae associated protein 2 antibody, caveolae associated 2 antibody, caveolae associated protein 2 S homeolog antibody, serum deprivation response antibody, caveolae associated protein 2b antibody, CAVIN2 antibody, Cavin2 antibody, cavin2.S antibody, SDPR antibody, cavin2b antibody

Background: SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.

Molecular Weight: Predicted: 22, 33, 43 kDa kDa

Observed: 30 kDa

Gene ID: 8436

NCBI Accession: NP_004648

UniProt: O95810