MKRN3 antibody (C-Term)

Catalog No. ABIN6992123

Product Details anti-MKRN3 Antibody

Target: MKRN3 (Makorin Ring Finger Protein 3 (MKRN3))

Binding Specificity: AA 400-450, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: MKRN3 antibody is human specific. MKRN3 antibody is predicted to not cross-react with other members of the MKRN protein family.

Purification: MKRN3 antibody is affinity chromatography purified via peptide column.

Immunogen: MKRN3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MKRN3. The immunogen is located within amino acids 400 - 450 of MKRN3.

Isotype: IgG

Application Details

Application Notes: MKRN3 antibody can be used for detection of MKRN3 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MKRN3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MKRN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for MKRN3

Target: MKRN3 (Makorin Ring Finger Protein 3 (MKRN3))

Alternative Name: MKRN3 (MKRN3 Products)

Synonyms: CPPB2 antibody, D15S9 antibody, RNF63 antibody, ZFP127 antibody, ZNF127 antibody, D7H15S9-1 antibody, Zfp127 antibody, makorin ring finger protein 3 antibody, makorin, ring finger protein, 3 antibody, MKRN3 antibody, Mkrn3 antibody

Background: The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome (1), but a deletion of the gene does not (2). A deficiency of MKRN3 has been shown to cause central precocious puberty in humans (3).

Molecular Weight: Predicted: 55 kDa

Observed: 55 kDa

Gene ID: 7681

NCBI Accession: NP_005655

UniProt: Q6NSB6