Caspase 8 antibody (AA 217-384)

Catalog No. ABIN6992495

This Rabbit Polyclonal antibody specifically detects Caspase 8 in FACS. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (AA 217-384) (ABIN6992495)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-Caspase 8 Antibody

Binding Specificity: AA 217-384

Purpose: Anti-Caspase 8 (CASP8) Polyclonal Antibody

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Caspase 8 (CASP8) corresdonding to Ser217~Asp384 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: For flow cytometry, the suggested use of this reagent is 1-5 μL per 10^6 cells in 100 μL volume. Optimal working dilutions could be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: Caspase 8

Background: CAP4, FLICE, MACH, MCH5, Cysteinyl Aspartate Specific Proteinases 8, Apoptotic cysteine protease, FADD-homologous ICE/ced-3-like protease, MORT1-associated ced-3 homolog

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades