NR3C2 antibody (AA 739-984)

Catalog No. ABIN7431818

The Rabbit Polyclonal anti-NR3C2 antibody (ABIN7431818) specifically detects NR3C2 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for NR3C2 antibody (AA 739-984) (ABIN7431818)

Target: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR3C2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NR3C2 Antibody

Binding Specificity: AA 739-984

Purpose: Polyclonal Antibody to Mineralocorticoid Receptor (MR)

Specificity: The antibody is a rabbit polyclonal antibody raised against MR. It has been selected for its ability to recognize MR in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Pig

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Mineralocorticoid Receptor (MR) corresdonding to Val739~Lys984 with N-terminal His and GST Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.32 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for NR3C2

Target: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Alternative Name: Mineralocorticoid Receptor

Background: NR3C2, MLR, MCR, Aldosterone Receptor, Nuclear Receptor Subfamily 3 Group C Member 2

UniProt: P08235

Pathways: ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway