Integrin beta 2 antibody (AA 124-363)

Catalog No. ABIN7438640

This anti-Integrin beta 2 antibody is a Rabbit Polyclonal antibody detecting Integrin beta 2 in WB, IHC, IP and ICC. Suitable for Human.

Quick Overview for Integrin beta 2 antibody (AA 124-363) (ABIN7438640)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Integrin beta 2 Antibody

Binding Specificity: AA 124-363

Purpose: Polyclonal Antibody to Integrin Beta 2 (CD18)

Specificity: The antibody is a rabbit polyclonal antibody raised against CD18. It has been selected for its ability to recognize CD18 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Integrin Beta 2 (CD18) corresdonding to Gly124~Leu363 with N-terminal His and GST Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: ITGb2, ITG-B2, LAD, LFA1, MAC1, LCAMB, MF17, LFAb, Complement Component 3 Receptor 3 And 4 Subunit, Lymphocyte Function-Associated Antigen 1, Macrophage Antigen 1

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation