CYP2D6 antibody (AA 236-472)

Catalog No. ABIN7437350

This Rabbit Polyclonal antibody specifically detects CYP2D6 in WB, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for CYP2D6 antibody (AA 236-472) (ABIN7437350)

Target: CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2D6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-CYP2D6 Antibody

Binding Specificity: AA 236-472

Purpose: Polyclonal Antibody to Cytochrome P450 2D6 (CYP2D6)

Specificity: The antibody is a rabbit polyclonal antibody raised against CYP2D6. It has been selected for its ability to recognize CYP2D6 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Pig, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Cytochrome P450 2D6 (CYP2D6) corresdonding to Leu236~Gln472 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.2-2 μg/mL,1:250-2500 Immunohistochemistry: 5-20 μg/mL,1:25-100 Immunocytochemistry: 5-20 μg/mL,1:25-100 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for CYP2D6

Target: CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))

Alternative Name: CYP2D6

Background: CYP2D, P450C2D, CPD6, CYP2DL1, P450-DB1, Cytochrome P450 Family 2 Subfamily D Polypeptide 6, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase

UniProt: P10635