ATR antibody (AA 2353-2644)

Catalog No. ABIN7443059

This anti-ATR antibody is a Rabbit Polyclonal antibody detecting ATR in WB, IP, ICC and IHC. Suitable for Human.

Quick Overview for ATR antibody (AA 2353-2644) (ABIN7443059)

Target: ATR (Ataxia Telangiectasia and Rad3 Related (ATR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATR antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Product Details anti-ATR Antibody

Binding Specificity: AA 2353-2644

Purpose: Polyclonal Antibody to Ataxia Telangiectasia And Rad3 Related Protein (ATR)

Specificity: The antibody is a rabbit polyclonal antibody raised against ATR. It has been selected for its ability to recognize ATR in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Ataxia Telangiectasia And Rad3 Related Protein (ATR) corresdonding to Ala2353~Met2644 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for ATR

Target: ATR (Ataxia Telangiectasia and Rad3 Related (ATR))

Alternative Name: Ataxia Telangiectasia And Rad3 Related Protein

Background: FRP1, SCKL, SCKL1, MEC1, FRAP-related protein 1, Serine/threonine-protein kinase ATR

UniProt: Q13535

Pathways: p53 Signaling, Apoptosis, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus