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FHIT antibody

The Rabbit Polyclonal anti-FHIT antibody has been validated for ELISA, WB and IHC. It is suitable to detect FHIT in samples from Human, Mouse and Rat.
Catalog No. ABIN7237004

Quick Overview for FHIT antibody (ABIN7237004)

Target

See all FHIT Antibodies
FHIT (Fragile Histidine Triad (FHIT))

Reactivity

  • 83
  • 23
  • 11
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Mouse, Rat

Host

  • 79
  • 9
Rabbit

Clonality

  • 78
  • 10
Polyclonal

Conjugate

  • 32
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This FHIT antibody is un-conjugated

Application

  • 42
  • 31
  • 26
  • 26
  • 12
  • 12
  • 7
  • 6
  • 4
  • 3
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant protein of human FHIT

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000, IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FHIT (Fragile Histidine Triad (FHIT))

    Alternative Name

    FHIT

    Background

    This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

    Molecular Weight

    17 kDa

    UniProt

    P49789
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