BAI1 antibody

Catalog No. ABIN7238702

The Rabbit Polyclonal anti-BAI1 antibody (ABIN7238702) specifically detects BAI1 in IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BAI1 antibody (ABIN7238702)

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAI1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-BAI1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human BAI1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAI1

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Alternative Name: ADGRB1

Background: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.

NCBI Accession: NP_001693

UniProt: O14514

Pathways: p53 Signaling