ZNF395 antibody

Catalog No. ABIN7239020

Product Details anti-ZNF395 Antibody

Target: ZNF395 (Zinc Finger Protein 395 (ZNF395))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF395 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ZNF395

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZNF395

Target: ZNF395 (Zinc Finger Protein 395 (ZNF395))

Alternative Name: ZNF395 (ZNF395 Products)

Synonyms: HDBP-2 antibody, HDBP2 antibody, HDRF-2 antibody, PBF antibody, PRF-1 antibody, PRF1 antibody, Si-1-8-14 antibody, sb:cb866 antibody, zgc:55309 antibody, si:ch211-89p3.1 antibody, si:ch211-223o11.1 antibody, ZNF395 antibody, pbf antibody, prf1 antibody, hdbp2 antibody, prf-1 antibody, si-1-8-14 antibody, BC053701 antibody, Gm910 antibody, si:ch211-63o20.5 antibody, wu:fa14e01 antibody, zgc:158367 antibody, zinc finger protein 395 antibody, zinc finger protein 395 S homeolog antibody, family with sequence similarity 49, member A antibody, zinc finger protein 395b antibody, zinc finger protein 395a antibody, ZNF395 antibody, znf395.S antibody, fam49a antibody, znf395 antibody, Zfp395 antibody, Znf395 antibody, znf395b antibody, znf395a antibody

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3'-CCGG-5' sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

NCBI Accession: NP_061130

UniProt: Q9H8N7