PGLYRP1 antibody

Catalog No. ABIN7001445

Product Details anti-PGLYRP1 Antibody

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGLYRP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human PGLYRP1

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PGLYRP1

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Alternative Name: PGLYRP1 (PGLYRP1 Products)

Synonyms: PGLYRP1 antibody, PGLYRP antibody, pgrp antibody, tag7 antibody, pgrps antibody, pglyrp antibody, pgrp-s antibody, tnfsf3l antibody, MGC108330 antibody, MGC108469 antibody, PGRP-SC1a antibody, si:dkey-113g17.4 antibody, si:ch211-202c21.3 antibody, PGRP antibody, PGRP-S antibody, PGRPS antibody, TAG7 antibody, TNFSF3L antibody, Pglyrp antibody, Tag7 antibody, Tasg7 antibody, Tnfsf3l antibody, Pgrp antibody, peptidoglycan recognition protein 1 antibody, peptidoglycan recognition protein 1 L homeolog antibody, peptidoglycan recognition protein 5 antibody, PGLYRP1 antibody, pglyrp1.L antibody, pglyrp1 antibody, pglyrp5 antibody, Pglyrp1 antibody

Background: Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-I and PGRP-I are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.

Molecular Weight: 22 kDa

NCBI Accession: NP_005082

UniProt: O75594

Pathways: Activation of Innate immune Response