PCDHGB5 antibody

Catalog No. ABIN7244762

Product Details anti-PCDHGB5 Antibody

Target: PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGB5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PCDHGB5

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDHGB5

Target: PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))

Alternative Name: PCDHGB5 (PCDHGB5 Products)

Synonyms: PCDH-GAMMA-B5 antibody, protocadherin gamma subfamily B, 5 antibody, PCDHGB5 antibody, Pcdhgb5 antibody

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

UniProt: Q9Y5G0