CEMIP antibody
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- Target See all CEMIP Antibodies
- CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CEMIP antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human CEMIP
- Isotype
- IgG
- Top Product
- Discover our top product CEMIP Primary Antibody
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- Application Notes
- IHC 1:100-1:300, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.68 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
- Alternative Name
- CEMIP (CEMIP Products)
- Synonyms
- CCSP1 antibody, TMEM2L antibody, 3110012M15Rik antibody, mKIAA1412 antibody, 12H19.01.T7 antibody, 6330404C01Rik antibody, AY007814 antibody, Kiaa1199 antibody, KIAA1199 antibody, cell migration inducing hyaluronan binding protein antibody, transmembrane protein 2 antibody, cell migration inducing protein, hyaluronan binding antibody, CEMIP antibody, Tmem2 antibody, TMEM2 antibody, Cemip antibody
- Background
- Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
- UniProt
- Q8WUJ3
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