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RFX6 antibody

RFX6 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7246697
  • Target See all RFX6 Antibodies
    RFX6 (Regulatory Factor X 6 (RFX6))
    Reactivity
    • 19
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 17
    • 2
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFX6 antibody is un-conjugated
    Application
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human RFX6
    Isotype
    IgG
    Top Product
    Discover our top product RFX6 Primary Antibody
  • Application Notes
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.96 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RFX6 (Regulatory Factor X 6 (RFX6))
    Alternative Name
    RFX6 (RFX6 Products)
    Synonyms
    MTFS antibody, RFXDC1 antibody, dJ955L16.1 antibody, 4930572O07Rik antibody, Rfxdc1 antibody, regulatory factor X6 antibody, regulatory factor X, 6 antibody, RFX6 antibody, Rfx6 antibody
    Background
    The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.
    UniProt
    Q8HWS3
    Pathways
    Carbohydrate Homeostasis
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