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GLI1 antibody

GLI1 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7248111
  • Target See all GLI1 Antibodies
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Reactivity
    • 85
    • 55
    • 35
    • 17
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    Human, Mouse
    Host
    • 72
    • 13
    • 3
    • 1
    Rabbit
    Clonality
    • 68
    • 21
    Polyclonal
    Conjugate
    • 42
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLI1 antibody is un-conjugated
    Application
    • 55
    • 20
    • 16
    • 14
    • 14
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human GLI1
    Isotype
    IgG
    Top Product
    Discover our top product GLI1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.08 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Alternative Name
    GLI1 (GLI1 Products)
    Synonyms
    GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
    Background
    GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 118 kDa

    UniProt
    P08151
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis
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