HAS1 antibody

Catalog No. ABIN7249004

The Rabbit Polyclonal anti-HAS1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect HAS1 in samples from Human and Mouse.

Quick Overview for HAS1 antibody (ABIN7249004)

Target: HAS1 (Hyaluronan Synthase 1 (HAS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-HAS1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human HAS1

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HAS1

Target: HAS1 (Hyaluronan Synthase 1 (HAS1))

Alternative Name: HAS1

Background: Hyaluronan or hyaluronic acid (HA) is a higHuman, Mouseolecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis.

Molecular Weight: 65 kDa

NCBI Accession: NP_001514

UniProt: Q92839

Pathways: Glycosaminoglycan Metabolic Process