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KRT17 antibody

KRT17 Reactivity: Human WB, IF, IHC (p), IP Host: Mouse Monoclonal 2K5 unconjugated
Catalog No. ABIN7250128
  • Target See all KRT17 Antibodies
    KRT17 (Keratin 17 (KRT17))
    Reactivity
    • 123
    • 47
    • 29
    • 18
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 100
    • 34
    Mouse
    Clonality
    • 87
    • 47
    Monoclonal
    Conjugate
    • 56
    • 16
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT17 antibody is un-conjugated
    Application
    • 102
    • 44
    • 38
    • 30
    • 27
    • 26
    • 22
    • 19
    • 18
    • 15
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Characteristics
    Monoclonal Antibody
    Purification
    Protein A purification
    Immunogen
    Synthetic Peptide
    Clone
    2K5
    Isotype
    IgG
    Top Product
    Discover our top product KRT17 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KRT17 (Keratin 17 (KRT17))
    Alternative Name
    CK-17 (KRT17 Products)
    Synonyms
    K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody
    Background
    May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
    Molecular Weight

    Observed_MW: 48 kDa

    Calculated_MW: 48 kDa

    UniProt
    Q04695
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