Integrin Alpha2b antibody

Catalog No. ABIN7250233

The Mouse Monoclonal anti-Integrin Alpha2b antibody is suitable to detect Integrin Alpha2b in samples from Human. It has been validated for IHC (p).

Quick Overview for Integrin Alpha2b antibody (ABIN7250233)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5D1

Product Details anti-Integrin Alpha2b Antibody

Characteristics: Monoclonal Antibody

Purification: Protein A purification

Immunogen: Synthetic Peptide

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Background: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

UniProt: P08514

Pathways: Integrin Complex