HSD11B1 antibody
Quick Overview for HSD11B1 antibody (ABIN7251895)
Target
See all HSD11B1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human HSD11B1
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Isotype
- IgG
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anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibody
HSD11B1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 201-292) antibodyHSD11B1 Reactivity: Human, Rat, Mouse, Horse ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (Internal Region) antibodyHSD11B1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Sheep, Cow, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2C10 unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (C-Term) antibodyHSD11B1 Reactivity: Human WB, IHC (p), ICC, IF, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) antibodyHSD11B1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- IHC 1:50-1:200, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.2 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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Alternative Name
- HSD11B1
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Background
- The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
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UniProt
- P28845
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
Target
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