WDSUB1 antibody

Catalog No. ABIN7254652

Product Details anti-WDSUB1 Antibody

Target: WDSUB1 (WD Repeat, Sterile alpha Motif and U-Box Domain Containing 1 (WDSUB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDSUB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human WDSUB1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WDSUB1

Target: WDSUB1 (WD Repeat, Sterile alpha Motif and U-Box Domain Containing 1 (WDSUB1))

Alternative Name: WDSUB1 (WDSUB1 Products)

Synonyms: WDSUB1 antibody, 1700048E19Rik antibody, 2610014F08Rik antibody, zgc:154085 antibody, ubox6 antibody, wdsam1 antibody, UBOX6 antibody, WDSAM1 antibody, WD repeat, sterile alpha motif and U-box domain containing 1 antibody, WD repeat, SAM and U-box domain containing 1 antibody, WD repeat, sterile alpha motif and U-box domain containing 1 S homeolog antibody, WDSUB1 antibody, wdsub1 antibody, Wdsub1 antibody, wdsub1.S antibody

Background: WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1,400 genes and comprises nearly 8 % of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 53 kDa

UniProt: Q8N9V3