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P2RX7 antibody
P2RX7
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-P2RX7 Antibody
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Target
See all P2RX7 Antibodies
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Reactivity
All reactivities for P2RX7 antibodies
Human, Mouse, Rat
Host
All hosts for P2RX7 antibodies
Rabbit
Clonality
All clonalities for P2RX7 antibodies
Polyclonal
Conjugate
All conjugates for P2RX7 antibodies
This P2RX7 antibody is un-conjugated
Application
All applications for P2RX7 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human P2RX7 (NP_002553.3).
Isotype
IgG
Top Product
Discover our top product P2RX7 Primary Antibody
Alternatives
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody
P2RX7
Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody
P2RX7
Reactivity: Human, Mouse, Rat
WB, IHC, FACS, IF, ICC, LCI
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for P2RX7
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Target
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Alternative Name
P2RX7 (P2RX7 Products )
Synonyms
p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Gene ID
5027
UniProt
Q99572
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Vesicle Exocytosis
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