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TLR3 antibody

TLR3 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255782
  • Target See all TLR3 Antibodies
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Reactivity
    • 98
    • 65
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 85
    • 31
    • 3
    • 2
    Rabbit
    Clonality
    • 88
    • 33
    Polyclonal
    Conjugate
    • 53
    • 18
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR3 antibody is un-conjugated
    Application
    • 85
    • 43
    • 38
    • 35
    • 23
    • 18
    • 15
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TLR3 (NP_003256.1).
    Isotype
    IgG
    Top Product
    Discover our top product TLR3 Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Alternative Name
    TLR3 (TLR3 Products)
    Synonyms
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    Background
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
    Gene ID
    7098
    UniProt
    O15455
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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