SHMT2 antibody

Catalog No. ABIN7255944

Product Details anti-SHMT2 Antibody

Target: SHMT2 (serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHMT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SHMT2 (NP_005403.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SHMT2

Target: SHMT2 (serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2))

Alternative Name: SHMT2 (SHMT2 Products)

Synonyms: GLYA antibody, SHMT antibody, 2700043D08Rik antibody, AA408223 antibody, AA986903 antibody, serine hydroxymethyltransferase 2 antibody, serine hydroxymethyltransferase 2 (mitochondrial) antibody, serine hydroxymethyltransferase 2 (mitochondrial) L homeolog antibody, serine hydroxymethyltransferase, mitochondrial-like antibody, SHMT2 antibody, Chro.80302 antibody, Shmt2 antibody, shmt2 antibody, shmt2.L antibody, SHMT antibody

Background: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 52 kDa

Calculated_MW: 53 kDa/54 kDa/55 kDa

Gene ID: 6472

UniProt: P34897