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- Target See all MOCOS Antibodies
- MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MOCOS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MOCOS (NP_060417.2).
- Isotype
- IgG
- Top Product
- Discover our top product MOCOS Primary Antibody
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anti-Molybdenum Cofactor Sulfurase (MOCOS) (AA 1-888) antibody
MOCOS Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2E8 unconjugated
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))
- Alternative Name
- MOCOS (MOCOS Products)
- Synonyms
- HMCS antibody, MCS antibody, MOS antibody, 1110018O12Rik antibody, DDBDRAFT_0217046 antibody, DDBDRAFT_0252757 antibody, DDB_0217046 antibody, DDB_0252757 antibody, Og antibody, im:7142948 antibody, mocos antibody, molybdenum cofactor sulfurase antibody, MOCOS antibody, Mocos antibody, AOR_1_1090144 antibody, mocos antibody, MCYG_05594 antibody, VDBG_04857 antibody, MGYG_02684 antibody, TERG_06775 antibody, mal antibody
- Background
- This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine.
- Molecular Weight
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Observed_MW: 98 kDa
Calculated_MW: 98 kDa
- Gene ID
- 55034
- UniProt
- Q96EN8
- Pathways
- Response to Water Deprivation, ER-Nucleus Signaling
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