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GSTM3 antibody

GSTM3 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7258332
  • Target See all GSTM3 Antibodies
    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
    Reactivity
    • 25
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 19
    • 6
    • 2
    Rabbit
    Clonality
    • 23
    • 4
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    This GSTM3 antibody is un-conjugated
    Application
    • 19
    • 11
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human GSTM3 (NP_000840.2).
    Isotype
    IgG
    Top Product
    Discover our top product GSTM3 Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
    Alternative Name
    GSTM3 (GSTM3 Products)
    Synonyms
    GST5 antibody, GSTB antibody, GSTM3-3 antibody, GTM3 antibody, Fsc2 antibody, mGSTM5 antibody, glutathione S-transferase mu 3 antibody, glutathione S-transferase Mu 3 antibody, glutathione S-transferase, mu 3 antibody, GSTM3 antibody, Gstm3 antibody, LOC479911 antibody
    Background
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.
    Gene ID
    2947
    UniProt
    P21266
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