Reticulon 3 antibody

Catalog No. ABIN7258404

Product Details anti-Reticulon 3 Antibody

Target: Reticulon 3 (RTN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human RTN3 (NP_006045.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: RTN3 (RTN3 Products)

Synonyms: ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody

Background: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

Molecular Weight:

Observed_MW: 26 kDa

Calculated_MW: 23 kDa/25 kDa/26 kDa/27 kDa/100 kDa/110 kDa/112 kDa

Gene ID: 10313

UniProt: O95197