ATP6V0C antibody

Catalog No. ABIN7259070

Product Details anti-ATP6V0C Antibody

Target: ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V0C antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human ATP6V0C (NP_001185498.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V0C

Target: ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))

Alternative Name: ATP6V0C (ATP6V0C Products)

Synonyms: ATP6C antibody, ATP6L antibody, ATPL antibody, VATL antibody, VPPC antibody, Vma3 antibody, Atp6c antibody, Atp6c2 antibody, Atp6l antibody, Atpl antibody, Atpl-rs1 antibody, PL16 antibody, CHUNP6904 antibody, atp6l antibody, atp6v0c antibody, cb993 antibody, fb57d09 antibody, wu:fb57d09 antibody, atp6c antibody, atpl antibody, ductin antibody, vatl antibody, vma3 antibody, PLP antibody, wu:fc74d11 antibody, zgc:111904 antibody, zgc:77708 antibody, ATPase H+ transporting V0 subunit c antibody, ATPase, H+ transporting, lysosomal V0 subunit C antibody, ATPase H+ transporting V0 subunit C antibody, ATPase, H+ transporting, lysosomal, V0 subunit ca antibody, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c antibody, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog antibody, V-type proton ATPase 16 kDa proteolipid subunit antibody, ATPase, H+ transporting, lysosomal, V0 subunit cb antibody, ATP6V0C antibody, Atp6v0c antibody, atp6v0ca antibody, atp6v0c antibody, atp6v0c.L antibody, LOC696755 antibody, atp6v0cb antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.

Gene ID: 527

UniProt: P27449

Pathways: Transition Metal Ion Homeostasis, Proton Transport