CYP11A1 antibody

Catalog No. ABIN7259586

Product Details anti-CYP11A1 Antibody

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP11A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CYP11A1 (NP_000772.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:20-1:50 IF 1:20-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP11A1

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Alternative Name: CYP11A1 (CYP11A1 Products)

Synonyms: CYP11A antibody, CYP11A1 antibody, CYPXIA1 antibody, P450SCC antibody, Cyp11a antibody, Cypxia1 antibody, D9Ertd411e antibody, P450scc antibody, Scc antibody, cscc antibody, P450(scc) antibody, SSC antibody, cytochrome P450 family 11 subfamily A member 1 antibody, cholesterol side-chain cleavage enzyme, mitochondrial-like antibody, cytochrome P450 cholesterol side-chain cleavage antibody, cytochrome P450, family 11, subfamily a, polypeptide 1 antibody, cytochrome P450, family 11, subfamily A, polypeptide 1 antibody, CYP11A1 antibody, LOC101827747 antibody, Cyp11a1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

Molecular Weight:

Observed_MW: 50 kDa

Calculated_MW: 42 kDa/60 kDa

Gene ID: 1583

UniProt: P05108

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin