PDE3A antibody
-
- Target See all PDE3A Antibodies
- PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PDE3A antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PDE3A (NP_000912.3).
- Isotype
- IgG
-
-
- Application Notes
- IHC 1:50-1:100 IF 1:50-1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))
- Alternative Name
- PDE3A (PDE3A Products)
- Background
- This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Gene ID
- 5139
- UniProt
- Q14432
- Pathways
- cAMP Metabolic Process
-