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CTCF antibody

KO Validated CTCF Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259885
  • Target See all CTCF Antibodies
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Reactivity
    • 58
    • 36
    • 31
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 8
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 38
    • 22
    Polyclonal
    Conjugate
    • 46
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CTCF antibody is un-conjugated
    Application
    • 40
    • 12
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody ist KO validated.
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Grade
    KO Validated
    Immunogen
    Recombinant protein of human CTCF.
    Isotype
    IgG
    Top Product
    Discover our top product CTCF Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Alternative Name
    CTCF (CTCF Products)
    Synonyms
    im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
    Background
    This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 140 kDa

    Calculated_MW: 83 kDa

    Gene ID
    10664
    UniProt
    P49711
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