RPL5 antibody

Catalog No. ABIN7260019

Product Details anti-RPL5 Antibody

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RPL5 (NP_000960.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RPL5

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Alternative Name: RPL5 (RPL5 Products)

Synonyms: DBA6 antibody, L5 antibody, U21RNA antibody, CG17489 antibody, Dmel\\CG17489 antibody, E-2d antibody, M(2)40B antibody, Rp L5 antibody, Rpl5 antibody, dRPL5 antibody, yip6 antibody, rpl5 antibody, wu:fj02g05 antibody, zgc:86854 antibody, mg:cb01f08 antibody, rpl5l antibody, zgc:56511 antibody, zgc:77176 antibody, ribosomal protein L5 antibody, 60S ribosomal protein L5 antibody, Ribosomal protein L5 antibody, ribosomal protein L5 L homeolog antibody, 50S ribosomal protein L5 antibody, ribosomal protein L5 S homeolog antibody, ribosomal protein L5b antibody, rpl5 antibody, ribosomal protein L5a antibody, Rpl5 antibody, RPL5 antibody, rpl-5 antibody, RpL5 antibody, rpl5.L antibody, rpl5 antibody, rpl5.S antibody, rpl5b antibody, rpl5a antibody

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene ID: 6125

UniProt: P46777