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SCNN1A antibody
SCNN1A
Reactivity: Rat, Human, Mouse
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SCNN1A Antibody
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Target
See all SCNN1A Antibodies
SCNN1A
(Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
Reactivity
All reactivities for SCNN1A antibodies
Rat, Human, Mouse
Host
All hosts for SCNN1A antibodies
Rabbit
Clonality
All clonalities for SCNN1A antibodies
Polyclonal
Conjugate
All conjugates for SCNN1A antibodies
This SCNN1A antibody is un-conjugated
Application
All applications for SCNN1A antibodies
Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human SCNN1A (NP_001029.1).
Isotype
IgG
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Discover our top product SCNN1A Primary Antibody
Alternatives
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Application Details
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Application Notes
IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SCNN1A
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Target
SCNN1A
(Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
Alternative Name
SCNN1A (SCNN1A Products )
Synonyms
BESC2 antibody, ENaCa antibody, ENaCalpha antibody, SCNEA antibody, SCNN1 antibody, ENaC antibody, Scnn1 antibody, mENaC antibody, SCNN1A antibody, alphaxENaC antibody, besc2 antibody, enaca antibody, scnn1 antibody, ENAC antibody, sodium channel epithelial 1 alpha subunit antibody, sodium channel, nonvoltage-gated 1 alpha antibody, sodium channel, non voltage gated 1 alpha subunit L homeolog antibody, Scnn1a antibody, SCNN1A antibody, scnn1a.L antibody
Background
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
6337
UniProt
P37088
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