PTPRN antibody

Catalog No. ABIN7262216

The Rabbit Polyclonal anti-PTPRN antibody is suitable to detect PTPRN in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for PTPRN antibody (ABIN7262216)

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTPRN Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PTPRN (NP_001186693.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRN

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Alternative Name: PTPRN

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 66 kDa

Calculated_MW: 96 kDa/102 kDa/105 kDa

Gene ID: 5798

UniProt: Q16849