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RBP3 antibody

RBP3 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7262218
  • Target See all RBP3 Antibodies
    RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))
    Reactivity
    Human, Mouse, Rat
    Host
    • 50
    • 5
    Rabbit
    Clonality
    • 51
    • 4
    Polyclonal
    Conjugate
    • 24
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBP3 antibody is un-conjugated
    Application
    • 43
    • 21
    • 20
    • 9
    • 8
    • 7
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human RBP3 (NP_002891.1).
    Isotype
    IgG
    Top Product
    Discover our top product RBP3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))
    Alternative Name
    RBP3 (RBP3 Products)
    Synonyms
    Irbp antibody, Rbp-3 antibody, D10S64 antibody, D10S65 antibody, D10S66 antibody, IRBP antibody, RBPI antibody, RP66 antibody, retinol binding protein 3 antibody, interphotoreceptor retinoid-binding protein antibody, retinol binding protein 3, interstitial antibody, rbp3 antibody, RBP3 antibody, glr2547 antibody, XOO2681 antibody, AMED_0162 antibody, ambt_08395 antibody, Rbp3 antibody
    Background
    Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38 % identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.
    Molecular Weight

    Observed_MW: 180 kDa

    Calculated_MW: 135 kDa

    Gene ID
    5949
    UniProt
    P10745
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